摘要：活化诱导的细胞死亡(AICD)是HIV感染中引起大量T细胞凋亡的重要机制之一，因而备受人们的关注。多种HIV蛋白产物都对AICD的发生有不同的作用，而机体免疫系统的激活状态等因素也直接影响AICD的发生和发展方向，最终导致患者Th/Ts比例倒置及Kaposi肉瘤发生等多种临床特征的出现。IL-16、高效抗逆转录病毒疗法(HAART)等对AICD的过程有不同的影响，从而实现抑制HIV感染和控制病程的效果。

一、HIV感染中的AICD现象
二、HIV感染中AICD的发生机制
1. HIV的蛋白产物
2. 激活的作用
3. 尚存的疑问
三、HIV感染中AICD的作用结果
四、临床应用及展望

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